Intralesional immunotherapy with purified protein derivative (PPD) for cryotherapy‐resistant warts

Background Cryotherapy and immunotherapeutic modalities elicit nonspecific immune response against the human papillomavirus. There is a paucity of literature on the effects of a sequential shift to immunotherapy in cryotherapy‐resistant warts. Aim To study the efficacy of intralesional purified prot...

Full description

Saved in:
Bibliographic Details
Published in:International journal of dermatology 2020-06, Vol.59 (6), p.726-729
Main Authors: Kaimal, Sowmya, Gopinath, Hima, Premalatha, Venkatesh
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Alphapapillomavirus - immunology
Child
Child, Preschool
Cryotherapy
Female
Follow-Up Studies
Human papillomavirus
Humans
Immune clearance
Immune response
Immune system
Immunotherapy
Immunotherapy - adverse effects
Immunotherapy - economics
Immunotherapy - methods
Injections, Intralesional
Male
Middle Aged
Proteins
Recurrence
Treatment Outcome
Tuberculin
Tuberculin - administration & dosage
Tuberculin - adverse effects
Tuberculin - economics
Warts
Warts - immunology
Warts - pathology
Warts - therapy
Warts - virology
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Cryotherapy and immunotherapeutic modalities elicit nonspecific immune response against the human papillomavirus. There is a paucity of literature on the effects of a sequential shift to immunotherapy in cryotherapy‐resistant warts. Aim To study the efficacy of intralesional purified protein derivative (PPD) immunotherapy in cryotherapy‐resistant warts. Methods Patients with cryotherapy‐recalcitrant cutaneous warts were given intralesional injections of PPD into the index warts (oldest or largest) at 2‐week intervals until complete clearance or up to a maximum of six injections. The response in the treated index and distant warts was defined as complete, partial, and no response (
ISSN:0011-9059
1365-4632
DOI:10.1111/ijd.14839