Evaluation of Acute Oral Toxicity of a Polyherbal Liver Tonic for Poultry

The current study was designed to evaluate the acute oral toxicity potential of Superliv Gold liquid (M/s Ayurvet Limited, Baddi, India) according to OECD 423 guidelines. Superliv Gold liquid is a polyherbal hepatoprotective and hepatoregenerative liver tonic for poultry. Nine female Swiss albino mi...

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Bibliographic Details
Published in:Biosciences, biotechnology research Asia biotechnology research Asia, 2020-03, Vol.17 (1), p.85-87
Main Authors: Hajare, Sunil, Suresh Ingole, Ranjit, Sunidhi, Sunidhi, Kotagiri, Ravikanth, Ganguly, Bhaskar
Format: Article
Language:English
Subjects:
Creatinine
Efficiency
Feeds
Gold
Laboratory animals
Liver
Mortality
Oral administration
Parameter estimation
Poultry
Toxicity
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Summary:The current study was designed to evaluate the acute oral toxicity potential of Superliv Gold liquid (M/s Ayurvet Limited, Baddi, India) according to OECD 423 guidelines. Superliv Gold liquid is a polyherbal hepatoprotective and hepatoregenerative liver tonic for poultry. Nine female Swiss albino mice were used for the study. Each animal served as its own control. Following the oral administration of the test substance, the animals were observed for manifestation of toxic effects and deaths. No toxic effects or mortalities were observed. The estimation of biochemical parameters (AST, ALT, ALP and creatinine) and histopathological studies also did not reveal any significant findings. Hence, Superliv Gold liquid was found to be safe for use.
ISSN:0973-1245
2456-2602
DOI:10.13005/bbra/2813