Die Ontogenese der Plattfische — außergewöhnliche Meeresbewohner

Flatfish are unique amongst fishes because of their extreme asymmetric body shape with both eyes on the upside and full depigmentation on the bottom side. During metamorphosis a primarily bilateral symmetric larvae turns into the flat adult body. Analysis of the whole genome sequence of the Japanese...

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Bibliographic Details
Published in:Biospektrum 2018-06, Vol.24 (4), p.361-364
Main Author: Schartl, Manfred
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Genomes
Genomik
Human Genetics
Life Sciences
Metamorphosis
Microbiology
Nucleotide sequence
Pharmacology/Toxicology
Retinoic acid
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Summary:Flatfish are unique amongst fishes because of their extreme asymmetric body shape with both eyes on the upside and full depigmentation on the bottom side. During metamorphosis a primarily bilateral symmetric larvae turns into the flat adult body. Analysis of the whole genome sequence of the Japanese flounder revealed that retinoic acid signalling is critically involved in several processes that underlie the morphogenetic changes during metamorphosis.
ISSN:0947-0867
1868-6249
DOI:10.1007/s12268-018-0929-2