Application of EPR Spectroscopy in the Study of Iron Metabolism in Parkinson’s Disease

—A brief review of the authors’ work on the use of low-temperature EPR spectroscopy in blood tests of patients with Parkinson’s disease and tissues of rat organs taken in experiments that simulate the early stages of parkinsonism is presented. An analysis of the obtained and published data suggests...

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Bibliographic Details
Published in:Biophysics (Oxford) 2020-03, Vol.65 (2), p.327-330
Main Authors: Rikhireva, G. T., Makletsova, M. G.
Format: Article
Language:English
Subjects:
Basal ganglia
Biological and Medical Physics
Biophysics
Brain diseases
Central nervous system diseases
Complex Systems Biophysics
Hemoglobin
Low temperature
Movement disorders
Neurodegenerative diseases
Parkinson's disease
Physics
Physics and Astronomy
Spectroscopy
Spectrum analysis
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Summary:—A brief review of the authors’ work on the use of low-temperature EPR spectroscopy in blood tests of patients with Parkinson’s disease and tissues of rat organs taken in experiments that simulate the early stages of parkinsonism is presented. An analysis of the obtained and published data suggests that the process of hemoglobin degradation can be included in the list of fundamental characteristics of the pathogenesis of Parkinson’s disease.
ISSN:0006-3509
1555-6654
DOI:10.1134/S0006350920020190