Synthesis and Antibacterial Activity Investigation of Novel Cuprous Oxide-Graphene Oxide Nanocomposites

Due to the increasing resistance of pathogens to antibiotics, novel antibacterial nanocomposite materials have been attracting increasing research interest. Herein, we report a facile synthetic method for a novel highly antibacterial nanocomposite based on graphene oxide (GO) nanosheets decorated wi...

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Bibliographic Details
Published in:Chemistry letters 2020-06, Vol.49 (6), p.693-696
Main Authors: Huang, Hua, Velmurugan, Murugan, Manibalan, Kesavan, Zhang, Qiang, Lu, Xinling, Wang, Yong, Lin, Jin-Ming
Format: Article
Language:English
Subjects:
Antibacterial materials
Antibiotics
Copper oxides
Dilution
E coli
Electron microscopy
Field emission microscopy
Field emission spectroscopy
Graphene
Microscopy
Nanocomposites
Photoelectrons
Spectrum analysis
X ray photoelectron spectroscopy
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Summary:Due to the increasing resistance of pathogens to antibiotics, novel antibacterial nanocomposite materials have been attracting increasing research interest. Herein, we report a facile synthetic method for a novel highly antibacterial nanocomposite based on graphene oxide (GO) nanosheets decorated with cuprous oxide by a two-step method. The as-prepared nanocomposites were comprehensively characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), energy-dispersive X-ray (EDX) spectroscopy, field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The nanocomposite was investigated for antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) using the medium dilution method and the disc diffusion method. The results showed that the synthesized Cu2O-GO has good antibacterial activities. At the nanocomposites concentration of 100 µg/mL, the inhibition rate against E. coli reached 68%, while the inhibition rate against. S. aureus reached 32%.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.200128