Deciphering the Enigma: NAP (CP201) the Active ADNP Drug Candidate Enters Cells by Dynamin-Associated Endocytosis

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Bibliographic Details
Published in:Journal of molecular neuroscience 2020-07, Vol.70 (7), p.993-998
Main Authors: Ivashko-Pachima, Yanina, Gozes, Illana
Format: Article
Language:English
Subjects:
ADNP protein
Amino Acid Motifs
Amyotrophic Lateral Sclerosis - prevention & control
Animals
Axonal Transport - drug effects
Biomedical and Life Sciences
Biomedicine
Cell Biology
Cell Line, Tumor
Disease Models, Animal
Dynamin
Dynamins - physiology
Endocytosis
Homeodomain Proteins
Hydrazones - pharmacology
Mice
Mice, Knockout
Microtubule-Associated Proteins - drug effects
Microtubule-Associated Proteins - metabolism
Microtubules - drug effects
Microtubules - metabolism
Microtubules - ultrastructure
Nerve Tissue Proteins - deficiency
Neurochemistry
Neurology
Neurons - drug effects
Neuroprotective Agents - pharmacokinetics
Neurosciences
Oligopeptides - pharmacokinetics
Parkinsonian Disorders - drug therapy
Proteomics
Tauopathies - drug therapy
Tauopathies - prevention & control
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Description
Summary:
ISSN:0895-8696
1559-1166
DOI:10.1007/s12031-020-01632-6