Milkweed scaffold: A new candidate for bone cell growth

This study aims to evaluate the potential of milkweed as potential candidate to construct biodegradable scaffold for bone regeneration. A mat made of milkweed, polyethylene, and polypropylene was treated with an atmospheric pressure plasma to functionalize the surface of the polymer assembly with ca...

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Bibliographic Details
Published in:International journal of polymeric materials 2020-09, Vol.69 (13), p.872-883
Main Authors: Soulié, Simon, Bilem, Ibrahim, Chevallier, Pascale, Elkoun, Saïd, Robert, Mathieu, Naudé, Nicolas, Laroche, Gaétan
Format: Article
Language:English
Subjects:
Asclepias syriaca L
Assembly
atmospheric pressure plasma
Biodegradability
bone cell growth
Carboxylic acids
Degradation
Engineering Sciences
milkweed
Polyethylenes
Polymers
Regeneration (physiology)
Scaffolds
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Summary:This study aims to evaluate the potential of milkweed as potential candidate to construct biodegradable scaffold for bone regeneration. A mat made of milkweed, polyethylene, and polypropylene was treated with an atmospheric pressure plasma to functionalize the surface of the polymer assembly with carboxylic acid groups, which enable to conjugate bioactive molecules, while accelerating the degradation of milkweed. Degradation tests demonstrated substantial decrease of the weight of the treated polymer mat as compared to untreated one. Biological assays revealed that the polymer assembly promoted preosteoblast MC3T3 cells recruitment with a significant enhancement observed on the RGD-grafted polymer mat.
ISSN:0091-4037
1563-535X
DOI:10.1080/00914037.2019.1626391