Isotretinoin-induced pruritic erythematous lesions and acute chest pain in a 15-year-old girl

Isotretinoin is widely used in the treatment of acne vulgaris for more than 30 years (1). In addition to its systemic side effects, isotretinoin may also cause mucocutaneous side effects including cheilitis, nasal hemorrhage, dry skin, itching, rash, pigmented purpuric dermatosis, dry nose, purpura,...

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Bibliographic Details
Published in:The American journal of emergency medicine 2020-05, Vol.38 (5), p.1043.e1-1043.e3
Main Authors: Alataş, Ömer Doğan, Alataş, Emine Tugba
Format: Article
Language:English
Subjects:
Acne
Acute coronary syndromes
Cardiovascular disease
Case reports
Chest
Coronary vessels
Drug dosages
Emergency medical care
Heart attacks
Hematology
Hemorrhage
Histamine
Laboratories
Lesions
Medical imaging
Pain
Patients
Photosensitivity
Pruritus
Purpura
Side effects
Thrombosis
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Summary:Isotretinoin is widely used in the treatment of acne vulgaris for more than 30 years (1). In addition to its systemic side effects, isotretinoin may also cause mucocutaneous side effects including cheilitis, nasal hemorrhage, dry skin, itching, rash, pigmented purpuric dermatosis, dry nose, purpura, and photosensitivity. We report a case of a 15-year-old girl given isotretinoin for severe acne vulgaris who developed pruritic erythematous lesions and chest pain 5 min after taking the first dose 20 mg of isotretinoin.
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2019.158479