Regulatory System of Lipid Peroxidation as a Basis for Ecological Testing

Model systems were proposed, using previously obtained experimental data, for investigating the mechanism of regulation of oxidative processes in lipids isolated from natural objects, preparations, and various components of aqueous medium. The models include low-temperature oxidation of methyl oleat...

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Bibliographic Details
Published in:Russian journal of physical chemistry. B 2020-05, Vol.14 (3), p.498-503
Main Authors: Shishkina, L. N., Kozlov, M. V., Mazaletskaya, L. I., Povkh, A. Yu, Shvydkiy, V. O., Sheludchenko, N. I.
Format: Article
Language:English
Subjects:
Aqueous solutions
Autoxidation
Biological activity
Chemical Physics of Environmental Processes
Chemistry
Chemistry and Materials Science
Computer simulation
Lecithin
Lipid peroxidation
Lipids
Low temperature
Model testing
Oxidation
Physical Chemistry
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Summary:Model systems were proposed, using previously obtained experimental data, for investigating the mechanism of regulation of oxidative processes in lipids isolated from natural objects, preparations, and various components of aqueous medium. The models include low-temperature oxidation of methyl oleate in a thin layer as a model system of lipid peroxidation in biological membranes; computer simulation to determine the involvement of lipids and biologically active substances at different stages of autoxidation; and model of spontaneous autoxidation of lecithin in aqueous solution to assess the ability of aqueous medium components to participate in the regulation of oxidative processes in biological systems.
ISSN:1990-7931
1990-7923
DOI:10.1134/S1990793120030240