A ninhydrin–thiosemicarbazone based highly selective and sensitive chromogenic sensor for Hg2+ and F− ions

• Published in: Journal of chemical sciences (Bangalore, India) India), 2020, Vol.132 (1), Article 89
• Main Authors: Raju, V, Kumar, R Selva, Kumar, S K Ashok, Madhu, G, Bothra, Shilpa, Sahoo, Suban K
• Format: Article
• Language: English
• Subjects: Aqueous solutions; Calcium nitrate; Chemical sensors; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Chemoreceptors; Color; Colorimetry; Ethylenediaminetetraacetic acids; Mercury (metal); Ninhydrin; NMR; Nuclear magnetic resonance; Reagents; Regular Article; Sensors; Silica gel; Silicon dioxide; Spectrum analysis; Toothpaste
• ISSN: 0974-3626; 0973-7103
• DOI: 10.1007/s12039-020-01799-w

This study demonstrates the design, synthesis and sensing applications of a simple and efficient chemosensor, 2-(1,3-dioxo-1H-inden-2(3H)-ylidene)hydrazinecarbothioamide ( R ) for quick detection of Hg 2+ and F − in aqueous media using a colorimetric test, UV–Vis spectral analysis, and silica gel support. Sensor R showed the typical absorption peak at 305 nm for Hg 2+ which is responsible for color change from yellow to colorless, while in the case of F − , R exhibits a major peak at 415 nm and a color change from yellow to red. The limit of detection (LOD) of R for the analysis of Hg 2+ was calculated as 1×10 −6 M while for F − , it was found to be 3.4×10 −7 M. The binding modes of R with Hg 2+ and F − have been investigated by the Job’s plot, Benesi–Hildebrand (BH) method, 1 H NMR, FTIR and theoretical studies. The sensor R was reversible after treating it with reagents such as EDTA and calcium nitrate solution after contacting with Hg 2+ and F − , respectively. The performance of R can be successfully applied for the analysis of F − contents present in toothpastes. Graphic abstract A simple and efficient receptor ninhydrin-based Schiff’s base ( R ) for quick detection of Hg 2+ and F − in aqueous medium using colorimetric and UV–Vis spectral analyses.