RETRACTED ARTICLE: Two novel nanostructured La(III) coordination polymers were synthesized by sonochemical: crystal structures along with anticancer activity on human nasopharyngeal carcinoma cells
The preparation and the structural characterization of two La(III)-based coordination polymers was described in this study, in which {[La(H 2 O)(BTCTB)]·2H 2 O} n ( 1 , H 3 BTCTB = 3,3′,3′′-[1,3,5‐benzenetriyltris(carbonyl amino)] three benzoic acid) and [(La 2 (TATAB) 2 )·4DMF·4H 2 O] n ( 2 , H 3 T...
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Published in: | Journal of the Iranian Chemical Society 2020, Vol.17 (9), p.2307-2316 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The preparation and the structural characterization of two La(III)-based coordination polymers was described in this study, in which {[La(H
2
O)(BTCTB)]·2H
2
O}
n
(
1
, H
3
BTCTB = 3,3′,3′′-[1,3,5‐benzenetriyltris(carbonyl amino)] three benzoic acid) and [(La
2
(TATAB)
2
)·4DMF·4H
2
O]
n
(
2
, H
3
TATAB = 4,4,4″s-triazine-1,3,5-triethyl-m-aminobenzoic acid) were prepared by means of two flexible tricarboxylic acid ligands with different joints and functional backbones. Moreover, a sonochemical synthesis way has been carried out to produce the nanostructures of complexes
1
and
2
. In addition, their anticancer activity was evaluated on nasopharyngeal carcinoma cells. Firstly, Cell Counting Kit-8 test kit was used to test the cancer cells proliferation after treated with nano
1
or
2
. Then, the Annexin V-FITC/PI test was performed and the percentage of the apoptotic cancer cells was determined after nano
1
and
2
treatment. Next, the ROS accumulation after nano
1
and
2
treatment was detected by DCFH-DA detection kit. Finally, the expression level of FHIT in nasopharyngeal carcinoma cells treated with nano
1
and
2
was evaluated via western blot. |
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ISSN: | 1735-207X 1735-2428 |
DOI: | 10.1007/s13738-020-01926-x |