Synthesis and Anticancer Activity of1,3,4-Oxadiazole-oxazolo[4,5-b]pyridine Derivatives

A number of 1,3,4-oxadiazole incorporated oxazolo[4,5-b]pyridine derivatives has been synthesized, characterized and tested for anticancer activity against four human cancer cell lines including breast cancer (MCF-7), lung cancer (A549), colon cancer (Colo-205), and ovarian cancer (A2780) using etop...

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Published in:Russian journal of general chemistry 2020-01, Vol.90 (7), p.1331-1335
Main Authors: Kokkiligadda Suresh Babu, Musunuri Sivanadh, Maiti Bhimcharan, Basaveswara, Rao M V, Gattu, Sridhar
Format: Article
Language:English
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Anticancer properties
Cancer
Colon
Derivatives
Oxadiazoles
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container_issue 7
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container_title Russian journal of general chemistry
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creator Kokkiligadda Suresh Babu
Musunuri Sivanadh
Maiti Bhimcharan
Basaveswara, Rao M V
Gattu, Sridhar
description A number of 1,3,4-oxadiazole incorporated oxazolo[4,5-b]pyridine derivatives has been synthesized, characterized and tested for anticancer activity against four human cancer cell lines including breast cancer (MCF-7), lung cancer (A549), colon cancer (Colo-205), and ovarian cancer (A2780) using etoposide as a standard drug. All products demonstrate good anticancer activity, several compounds can be considered as promising anticancer agents.
doi_str_mv 10.1134/S107036322007021X
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subjects Anticancer properties
Cancer
Colon
Derivatives
Oxadiazoles
title Synthesis and Anticancer Activity of1,3,4-Oxadiazole-oxazolo[4,5-b]pyridine Derivatives
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