Disparate histopathology of sebaceous adenitis in a rabbit

A 13-month-old, spayed, female rex rabbit presented with mildly pruritic, progressive patches of alopecia, erythema and scaling of the head, trunk and legs of five months’ duration. Initial skin biopsy was consistent with cutaneous epitheliotropic lymphoma, but a follow-up skin biopsy and response t...

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Bibliographic Details
Published in:Veterinary record case reports 2020-09, Vol.8 (3), p.n/a
Main Authors: Heinrich, Nicole A, Chamroeun, Douglas, Locke, Erin
Format: Article
Language:English
Subjects:
Alopecia
Baldness
Biopsy
Case reports
Dermatitis
dermatology
Erythema
Hair
Histology
Histopathology
Lymphocytes
Lymphoma
Pruritus
Rabbits
Skin
Skin diseases
Triglycerides
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Summary:A 13-month-old, spayed, female rex rabbit presented with mildly pruritic, progressive patches of alopecia, erythema and scaling of the head, trunk and legs of five months’ duration. Initial skin biopsy was consistent with cutaneous epitheliotropic lymphoma, but a follow-up skin biopsy and response to therapy revealed that the rabbit actually had sebaceous adenitis. Nearly one year after presentation, the rabbit’s clinical signs remained well controlled. This case demonstrates the importance of interpreting histopathology in light of history, physical examination, supportive tests and response to therapy. It also demonstrates how cutaneous lesions may evolve over time and that serial biopsies may be required to achieve a diagnosis. Finally, this case suggests that there may be histopathological overlap between cutaneous epitheliotropic lymphoma and sebaceous adenitis in rabbits.
ISSN:2052-6121
2052-6121
DOI:10.1136/vetreccr-2020-001128