Clinical features of Behcet’s disease in Mongolia: a multicenter study

• Published in: Clinical rheumatology 2020-09, Vol.39 (9), p.2697-2706
• Main Authors: Balt, Javzandulam, Jamyanjav, Baasankhuu, Jav, Sarantuya, Dandii, Zulgerel, Ganbold, Chimedlkhamsuren, Horie, Yukihiro, Lennikov, Anton, Uehara, Osamu, Ohno, Shigeaki, Kitaichi, Nobuyoshi
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Behcet Syndrome - complications; Behcet Syndrome - diagnosis; Behcet Syndrome - epidemiology; Behcet's syndrome; Child; Environmental conditions; Epididymitis; Eye; Female; Females; Headache; Humans; Male; Males; Medicine; Medicine & Public Health; Middle Aged; Mongolia - epidemiology; Original Article; Patients; Prognosis; Rheumatology; Sex differences; Skin diseases; Skin lesions; Stomatitis, Aphthous; Thrombosis; Ulcers; Vasculitis; Vein & artery diseases; Young Adult
• ISSN: 0770-3198; 1434-9949
• DOI: 10.1007/s10067-020-05019-1

Objective The aim of the present study is to investigate the clinical features of patients with Behcet’s disease (BD) in Mongolia. Methods Patients were identified and examined from six medical institutions in Mongolia from January 2015 to January 2019. BD was diagnosed according to the diagnostic criteria for BD established by the International Study Group. Results There were sixty-five patients (22 males and 43 females) recoded, the ratio of 1:1.95, with a marked female predominance. The age of disease onset was 22.2 ± 10.0 (mean ± SD), ranging from 11 to 66 years old. Oral aphthous ulcers, ocular lesions, skin lesions, genital ulcers, pathergy test positivity, articular lesions, superficial vasculitis, deep vein thrombosis, and epididymitis (male only) were observed in 100.0%, 63.1%, 81.5%, 89.2%, 7.7%, 86.2%, 32.3%, 4.6%, and 13.6% of the patients, respectively. The incidence of poor visual prognosis, ≤ 20/200, was significantly higher in males than in females (31.8 vs. 9.3%, incidence rate ratio 4.55 (95% CI 1.16–17.82), p