Rapid Green Synthesis of Silver Nanoparticles Using Ethiopian Cactus Pear Fruit Peel Infusions and Evaluation of Its In Vitro Clinical Potentials

In the current study, the Ethiopian cactus pear fruit peel infusions were used as a phytoreducing agent to fabricate silver nanoparticles (CPFP-AgNPS). The formation of AgNPS in 7 min was confirmed by Ultra UV–Vis spectral portrait. The average size range (20–60 nm), the composition of silver elemen...

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Bibliographic Details
Published in:Journal of inorganic and organometallic polymers and materials 2020-09, Vol.30 (9), p.3832-3836
Main Authors: Kamaraj, M., Nithya, T. G., Santhosh, P., Mulugeta, Kidist
Format: Article
Language:English
Subjects:
Anticancer properties
Chemistry
Chemistry and Materials Science
Communication
Crystal structure
E coli
Inorganic Chemistry
Nanoparticles
Organic Chemistry
Polymer Sciences
Salmonella
Silver
X ray spectra
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Summary:In the current study, the Ethiopian cactus pear fruit peel infusions were used as a phytoreducing agent to fabricate silver nanoparticles (CPFP-AgNPS). The formation of AgNPS in 7 min was confirmed by Ultra UV–Vis spectral portrait. The average size range (20–60 nm), the composition of silver element and crystal structure of the CPFP-AgNPS was established by transmission electron microscopy, energy dispersive X-ray spectra and X-ray diffraction analysis respectively. The CPFP-AgNPS exhibited greater inhibition (81.92%) on 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical assay. The antibacterial activity of CPFP-AgNPS was high in the order against E.coli  >  Salmonella spp. >  Bacillus spp. >  Pseudomonas spp. >  Staphylococcus spp. respectively. The CPFP-AgNPS also showed effective anticancer activity against human cervix epithelioid carcinoma cell lines with an IC 50 value of 74.26 ± 0.25 µg mL −1 /24 h. In short, the findings highlighted the effectiveness of CPFP-AgNPS on potential therapeutic applications.
ISSN:1574-1443
1574-1451
DOI:10.1007/s10904-020-01549-y