Emodin-Containing MCM-41 Type Mesoporous Silica Nanoparticle Drug Delivery System

With the aim of developing drug delivery systems, it was shown that nanoparticles of mesoporous silica molecular sieve MCM-41 with average size 100-150 nm and specific surface 655 m 2 /g could include 202 mg of emodin per one gram of the carrier and release more than 85% of this compound at pH 8 dur...

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Bibliographic Details
Published in:Theoretical and experimental chemistry 2020-07, Vol.56 (3), p.174-182
Main Authors: dos Santos, I. M. D., Pereira, S. P., Mezacasa, A. V., Caceres, O. I. A., Timoteo, F., Lopes, A. S., del Pino, K. F., Duarte, A. P., Cardoso, T. F. M., de Castro, G. R., Rashid, H. U., Martines, M. A. U.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Drug delivery systems
Drugs
Molecular sieves
Nanoparticles
Silica
Silicon dioxide
Tin
Vehicles
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Summary:With the aim of developing drug delivery systems, it was shown that nanoparticles of mesoporous silica molecular sieve MCM-41 with average size 100-150 nm and specific surface 655 m 2 /g could include 202 mg of emodin per one gram of the carrier and release more than 85% of this compound at pH 8 during 48 h.
ISSN:0040-5760
1573-935X
DOI:10.1007/s11237-020-09649-z