Novel dose escalation to predict treatment with hydroxyurea (NDEPTH): A randomized controlled trial of a dose‐prediction equation to determine maximum tolerated dose of hydroxyurea in pediatric sickle cell disease

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Published in:American journal of hematology 2020-09, Vol.95 (9), p.E242-E244
Main Authors: George, Alex, Dinu, Bogdan, Estrada, Norma, Minard, Charles G., Hurwitz, Richard, Mahoney, Donald H., Yates, Amber M., Vaughan, Mary, Carmouche, Alaundra, Airewele, Gladstone, Kirk, Susan E., Fasipe, Titilope, Uwaezuoke, Precious, Ware, Russell E.
Format: Article
Language:English
Subjects:
Adolescent
Anemia, Sickle Cell - drug therapy
Anemia, Sickle Cell - mortality
Child
Female
Hematology
Humans
Hydroxyurea
Hydroxyurea - administration & dosage
Hydroxyurea - adverse effects
Male
Maximum Tolerated Dose
Sickle cell disease
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cited_by cdi_FETCH-LOGICAL-c3883-c8e8d8f49750b6ed633840ab59f3a25cb2f01db4fb940f54e762fc204d92e8b3
cites cdi_FETCH-LOGICAL-c3883-c8e8d8f49750b6ed633840ab59f3a25cb2f01db4fb940f54e762fc204d92e8b3
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container_issue 9
container_start_page E242
container_title American journal of hematology
container_volume 95
creator George, Alex
Dinu, Bogdan
Estrada, Norma
Minard, Charles G.
Hurwitz, Richard
Mahoney, Donald H.
Yates, Amber M.
Vaughan, Mary
Carmouche, Alaundra
Airewele, Gladstone
Kirk, Susan E.
Fasipe, Titilope
Uwaezuoke, Precious
Ware, Russell E.
description
doi_str_mv 10.1002/ajh.25883
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ispartof American journal of hematology, 2020-09, Vol.95 (9), p.E242-E244
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1096-8652
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source Wiley-Blackwell Read & Publish Collection
subjects Adolescent
Anemia, Sickle Cell - drug therapy
Anemia, Sickle Cell - mortality
Child
Female
Hematology
Humans
Hydroxyurea
Hydroxyurea - administration & dosage
Hydroxyurea - adverse effects
Male
Maximum Tolerated Dose
Sickle cell disease
title Novel dose escalation to predict treatment with hydroxyurea (NDEPTH): A randomized controlled trial of a dose‐prediction equation to determine maximum tolerated dose of hydroxyurea in pediatric sickle cell disease
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