Assessing the efficiency of using the mineral complex based on Nanopowders of metals in Experimental Post haemorrhagic Anemia in White Rats

The article discusses the results of assessing the efficiency of using the mineral complex based on nanopowders of iron, zinc, and copper for the morphological and biochemical parameters of blood on the background of modeling iron deficiency anemia in white rats. The statistically significant effect...

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Published in:Research journal of pharmacy and technology 2020, Vol.13 (7), p.3221-3226
Main Authors: Andreeva, E. Yu, Rodionova, T. N., Zabelina, M. V., Shalaeva, S. S., Krivenko, D. V., Polozyuk, O. N.
Format: Article
Language:English
Subjects:
Anemia
Bioavailability
Efficiency
Enzymes
Experiments
Hemoglobin
Iron
Laboratory animals
Metals
Morphology
Nanomaterials
Nanoparticles
Oxidative stress
Zinc
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container_end_page 3226
container_issue 7
container_start_page 3221
container_title Research journal of pharmacy and technology
container_volume 13
creator Andreeva, E. Yu
Rodionova, T. N.
Zabelina, M. V.
Shalaeva, S. S.
Krivenko, D. V.
Polozyuk, O. N.
description The article discusses the results of assessing the efficiency of using the mineral complex based on nanopowders of iron, zinc, and copper for the morphological and biochemical parameters of blood on the background of modeling iron deficiency anemia in white rats. The statistically significant effect of the studied preparation indicates the non-uniform recovery dynamics of the morphological parameters of the blood of white rats in various experimental groups. Copper and zinc should be considered in more detail since they have common grounds with iron in maintaining the homeostasis in the organism: they participate in building enzymes of the anti-oxidative stress and are at the same time involved in the processes of hematopoiesis and functioning of the immune system2. Zinc and iron are characterized by antagonistic interactions; however, many ions of trivalent iron may lead to the development of the oxidative stress, on which zinc has a direct effect, being part of the enzymes that catalyze the process of lipid peroxidation4.
doi_str_mv 10.5958/0974-360X.2020.00570.3
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subjects Anemia
Bioavailability
Efficiency
Enzymes
Experiments
Hemoglobin
Iron
Laboratory animals
Metals
Morphology
Nanomaterials
Nanoparticles
Oxidative stress
Zinc
title Assessing the efficiency of using the mineral complex based on Nanopowders of metals in Experimental Post haemorrhagic Anemia in White Rats
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