Molecular Identification, Metabolites profiling, Anti-breast cancer, Anti-colorectal cancer, and antioxidant potentials of Streptomyces zaomyceticus AA1 isolated from a remote bat cave in Egypt

[...]screening for new actinomycetes isolates was conducted from soil containing bat faeces collected from a remote cave located near Asyut Governorate, Egypt. According to the world health organization reports[1], cancer is one of the leading causes of death globally. Actinomycetes are a family of...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2020-07, Vol.13 (7), p.3072-3080
Main Authors: Elkhateeb, Waill A., Mohamed, Mohamed A., Fayad, Walid, Emam, Mahmoud, Nafady, Ibrahim M., Daba, Ghoson M.
Format: Article
Language:English
Subjects:
Antibiotics
Antioxidants
Breast cancer
Cancer therapies
Colorectal cancer
Cytotoxicity
Data analysis
Deoxyribonucleic acid
DNA
Fermentation
Gene amplification
Metabolites
Software
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Summary:[...]screening for new actinomycetes isolates was conducted from soil containing bat faeces collected from a remote cave located near Asyut Governorate, Egypt. According to the world health organization reports[1], cancer is one of the leading causes of death globally. Actinomycetes are a family of mycelial bacteria famous as rich sources of effective classes of antibiotics, such as rifamycins, ß-lactams, aminoglycosides, tetracyclines, glycopeptides, and macrolides[2,3]. [...]actinomycetes exhibited other promising biological activities such as anticancer, antifungal, and immunosuppressant agents[4-8]. [...]the aim of this study is to isolate and identify new actinomycetes isolates from novel sources showing potent anti-cancer activities. 2.MATERIALS AND METHODS: 2.1.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2020.00545.4