Floating Drug Delivery an Emerging Technology with Promising Market value

Oral drug distribution method is the maximum favored method of drug distribution system owing to easiness of drug administration due to low price therapy, flexibility in preparations and patient's compliance1. Floating drug delivery system or hydro dynamically balance systems consume bulk densi...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2020, Vol.13 (6), p.3014-3020
Main Authors: Devendiran, B, Mothilal, M, Damodharan, N
Format: Article
Language:English
Subjects:
Abdomen
Bioavailability
Drug delivery systems
Drug dosages
Plasma
Polymers
Polyvinyl alcohol
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Summary:Oral drug distribution method is the maximum favored method of drug distribution system owing to easiness of drug administration due to low price therapy, flexibility in preparations and patient's compliance1. Floating drug delivery system or hydro dynamically balance systems consume bulk density lower than gastrointestinal fluid and remain buoyant on the abdominal without disturbing the 'gastrointestinal releasing rate' as a prolonged and predictable time. Excipients are use most commonly for non-effervescent systems include calcium chloride, sodium alginate, agar, carbopol, polyvinyl acetate, hydroxypropyl methyl cellulose and polycarbonate15. 2.Dosage forms of multiple part floating: Multi part dosage forms reduce the GI toxic effect and increasing the therapeutic and patient compliance16. a) Effervescent system (generating gas system): A multiple part dosage system contains calcium alginate core and calcium alginate/Polyvinyl alcohol are divided through an air section was organized.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2020.00533.8