Sesame Seed and Its Fractions for Improving Oxidative Stress in Adults: A Systematic Review and Meta-analysis of Controlled Clinical Trials

It is proposed that sesame products affect oxidative stress, although the findings were inconsistent. This study aimed to summarize the effect of sesame seed and its fractions on oxidative stress parameters in human adults using systematic review and meta-analysis. PubMed, Scopus, ISI Web of Science...

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Published in:Food reviews international 2020-11, Vol.36 (8), p.727-744
Main Authors: Moghtaderi, Fatemeh, Ramezani-Jolfaie, Nahid, Raeisi-Dehkordi, Hamidreza, Salehi-Abargouei, Amin
Format: Article
Language:English
Subjects:
Adults
Antioxidants
Ascorbic acid
Carotene
Catalase
Clinical trials
Confidence intervals
Consumption
Glutathione
Glutathione peroxidase
Malondialdehyde
Meta-analysis
Oxidative stress
Peroxidase
Search engines
Seeds
Sesame fractions
Sesame seed
Sesamum
Superoxide dismutase
Supplements
Systematic Review
Tocopherol
Vegetable oils
Vitamin E
β-Carotene
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description It is proposed that sesame products affect oxidative stress, although the findings were inconsistent. This study aimed to summarize the effect of sesame seed and its fractions on oxidative stress parameters in human adults using systematic review and meta-analysis. PubMed, Scopus, ISI Web of Science and Google Scholar were searched up to April 2018 to identify relevant controlled clinical trials. Random effects model was used for calculating the overall effects. Fifteen clinical trials were eligible. Meta-analyses revealed that sesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants (P
doi_str_mv 10.1080/87559129.2019.1683744
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It was shown that MDA levels significantly decreases only when sesame seeds were used for supplementation (Hedges' g = −0.74, 95% CI: −1.11, −0.36, P &lt; .001). Sesame consumption is associated with improved oxidative status. 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subjects Adults
Antioxidants
Ascorbic acid
Carotene
Catalase
Clinical trials
Confidence intervals
Consumption
Glutathione
Glutathione peroxidase
Malondialdehyde
Meta-analysis
Oxidative stress
Peroxidase
Search engines
Seeds
Sesame fractions
Sesame seed
Sesamum
Superoxide dismutase
Supplements
Systematic Review
Tocopherol
Vegetable oils
Vitamin E
β-Carotene
title Sesame Seed and Its Fractions for Improving Oxidative Stress in Adults: A Systematic Review and Meta-analysis of Controlled Clinical Trials
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