Oxidative stress, hemato-immunological, and intestinal morphometry changes induced by ochratoxin A in APRI rabbits and the protective role of probiotics

This work studied the protective effects of Aspergillus awamori against ochratoxin A (OTA)-induced toxicity in APRI maternal line rabbits. A total number of 48 APRI line weanling rabbits (5 weeks) were divided into 4 groups (12 rabbits each) and fed the basal diet, 30 ppb/kg diet of OTA, 1 g/kg diet...

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Bibliographic Details
Published in:Environmental science and pollution research international 2020-10, Vol.27 (28), p.35439-35448
Main Authors: El-Deep, Mahmoud H., Amber, Khairy A., Elgendy, Salwa, Dawood, Mahmoud A. O., Elwakeel, Enas M., Paray, Bilal Ahamad
Format: Article
Language:English
Subjects:
Albumins
Alkaline phosphatase
Animal Feed - analysis
Animals
Aquatic Pollution
Aspartate aminotransferase
Atmospheric Protection/Air Quality Control/Air Pollution
Body weight
Catalase
Conversion ratio
Creatinine
Diet
Digestibility
Earth and Environmental Science
Ecotoxicology
Environment
Environmental Chemistry
Environmental Health
Environmental science
Erythrocytes
Feed conversion
Hemoglobin
Immunology
Intestine
Lipids
Malondialdehyde
Morphometry
Ochratoxin A
Ochratoxins
Oxidative Stress
Phagocytes
Probiotics
Proteins
Rabbits
Research Article
Superoxide dismutase
Toxicity
Urea
Waste Water Technology
Water Management
Water Pollution Control
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Summary:This work studied the protective effects of Aspergillus awamori against ochratoxin A (OTA)-induced toxicity in APRI maternal line rabbits. A total number of 48 APRI line weanling rabbits (5 weeks) were divided into 4 groups (12 rabbits each) and fed the basal diet, 30 ppb/kg diet of OTA, 1 g/kg diet of A. awamori , and a mixture of OTA and A. awamori for 8 weeks. OTA reduced the final body weight and weight gain as well as the intestinal villi length and thickness, whereas increased the feed intake and feed conversion ratio. Rabbits fed diets with OTA showed significantly reduced crude protein, lipids, and fibers apparent digestibility coefficients ( P  
ISSN:0944-1344
1614-7499
DOI:10.1007/s11356-020-09837-3