Relation between PSA density and histologically proven chronic prostatitis

Aim: Prostate-specific antigen (PSA) may elevate in case of prostate cancer, benign prostatic hyperplasia (BPH) as well as chronic prostatitis. In chronic prostatitis and BPH distinction PSA, free / total PSA ratio isn’t usefull. The aim of this study is to question the place of PSA density in the d...

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Published in:Gülhane Tip Dergisi 2013-03, Vol.55 (1), p.18
Main Authors: Malkoç, Ercan, Ateş, Ferhat, Uğuz, Sami, Dursun, Furkan, Ahmet Kenan Karademir, Adayener, Cüneyt, Baykal, Kadir Vehbi
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Language:eng ; tur
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Biopsy
Prostate cancer
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container_issue 1
container_start_page 18
container_title Gülhane Tip Dergisi
container_volume 55
creator Malkoç, Ercan
Ateş, Ferhat
Uğuz, Sami
Dursun, Furkan
Ahmet Kenan Karademir
Adayener, Cüneyt
Baykal, Kadir Vehbi
description Aim: Prostate-specific antigen (PSA) may elevate in case of prostate cancer, benign prostatic hyperplasia (BPH) as well as chronic prostatitis. In chronic prostatitis and BPH distinction PSA, free / total PSA ratio isn’t usefull. The aim of this study is to question the place of PSA density in the distinction of BPH and prostatitis. Materials and Methods: In our clinic BPH pre - diagnosed, data of transurethral resection of prostate (TUR-P) performed and histologically diagnosed as no chronic prostatitis observed (group 1), with TUR-P performed but chronic prostatitis diagnosed (group 2) patients were retrospectively analyzed. The age, PSA, biopsy history, prostate size and PSA density (PSAD = PSA level / prostate volume) of patients were recorded. Results: Chronic prostatitis was determined in 100 of 641 patients (%15. 6). Biopsy before TUR-P was performed to 28 patients in the chronic prostatitis group, and 27 patients in BPH group (n=100) and in only 4 patients (%14. 3) in the chronic prostatitis group pathological evidence of prostatitis was determined. PSA (p
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In chronic prostatitis and BPH distinction PSA, free / total PSA ratio isn’t usefull. The aim of this study is to question the place of PSA density in the distinction of BPH and prostatitis. Materials and Methods: In our clinic BPH pre - diagnosed, data of transurethral resection of prostate (TUR-P) performed and histologically diagnosed as no chronic prostatitis observed (group 1), with TUR-P performed but chronic prostatitis diagnosed (group 2) patients were retrospectively analyzed. The age, PSA, biopsy history, prostate size and PSA density (PSAD = PSA level / prostate volume) of patients were recorded. Results: Chronic prostatitis was determined in 100 of 641 patients (%15. 6). Biopsy before TUR-P was performed to 28 patients in the chronic prostatitis group, and 27 patients in BPH group (n=100) and in only 4 patients (%14. 3) in the chronic prostatitis group pathological evidence of prostatitis was determined. PSA (p&lt;.001) and prostate volume (p=0.017) was larger in the chronic prostatitis group when compared with the BPH group. Also PSA density (p&lt;.001) was higher. Conclusion: PSA density was higher in patients with chronic prostatitis.</description><identifier>ISSN: 1302-0471</identifier><identifier>EISSN: 2146-8052</identifier><identifier>DOI: 10.5455/gulhane.15744</identifier><language>eng ; tur</language><publisher>Ankara: Gulhane Medical Journal</publisher><subject>Biopsy ; Prostate cancer</subject><ispartof>Gülhane Tip Dergisi, 2013-03, Vol.55 (1), p.18</ispartof><rights>2013. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). 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In chronic prostatitis and BPH distinction PSA, free / total PSA ratio isn’t usefull. The aim of this study is to question the place of PSA density in the distinction of BPH and prostatitis. Materials and Methods: In our clinic BPH pre - diagnosed, data of transurethral resection of prostate (TUR-P) performed and histologically diagnosed as no chronic prostatitis observed (group 1), with TUR-P performed but chronic prostatitis diagnosed (group 2) patients were retrospectively analyzed. The age, PSA, biopsy history, prostate size and PSA density (PSAD = PSA level / prostate volume) of patients were recorded. Results: Chronic prostatitis was determined in 100 of 641 patients (%15. 6). Biopsy before TUR-P was performed to 28 patients in the chronic prostatitis group, and 27 patients in BPH group (n=100) and in only 4 patients (%14. 3) in the chronic prostatitis group pathological evidence of prostatitis was determined. PSA (p&lt;.001) and prostate volume (p=0.017) was larger in the chronic prostatitis group when compared with the BPH group. Also PSA density (p&lt;.001) was higher. 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Prostate cancer
title Relation between PSA density and histologically proven chronic prostatitis
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