Synthesis of substituted pyrimidine using ZnFe2O4 nanocatalyst via one pot multi‐component reaction ultrasonic irradiation

A highly efficient, eco‐friendly, recyclable heterogeneous ZnFe2O4 nanocatalyzed synthesis of 2‐amino‐4‐substituted 1,4‐dihydrobenzo[4,5]imidazo[1,2‐a]pyrimidine‐3‐carbonitrile (4a‐j) derivatives via one pot multicomponent reaction of benzimidazole (1), substituted aromatic aldehyde (2a‐j) and malon...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry 2020-09, Vol.57 (9), p.3326-3333
Main Authors: Chavan, Pravin, Bangale, Sachin, Pansare, Dattatraya, Shelke, Rohini, Jadhav, Shivaji, Tupare, Shrikrushna, Kamble, Dhanraj, Rai, Megha
Format: Article
Language:English
Subjects:
Aldehydes
Malononitrile
Reaction time
Substitutes
Synthesis
Zinc ferrites
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Summary:A highly efficient, eco‐friendly, recyclable heterogeneous ZnFe2O4 nanocatalyzed synthesis of 2‐amino‐4‐substituted 1,4‐dihydrobenzo[4,5]imidazo[1,2‐a]pyrimidine‐3‐carbonitrile (4a‐j) derivatives via one pot multicomponent reaction of benzimidazole (1), substituted aromatic aldehyde (2a‐j) and malononitrile (3) under ultrasonic irradiations. Significance of this synthetic approach is short reaction time, easy handling, simplicity, efficiency, high yield, and recoverable catalyst.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.4048