Focal seizures with a migrating aspect in infants treated with beta-lactam antibiotics – Report of two cases

Seizures caused by beta-lactam antibiotics are relatively rare. However, they represent a clinically significant phenomenon and have been widely reported in all age groups. Here we describe two infants presenting subtle multifocal seizures with a migrating aspect on EEG during beta-lactam antibiotic...

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Bibliographic Details
Published in:Neurophysiologie clinique 2020-04, Vol.50 (2), p.81-86
Main Authors: Minh Nguyen, Kien, Bustarret, Olivier, Jugie, Myriam, Nabbout, Rima, Kaminska, Anna, Eisermann, Monika
Format: Article
Language:English
Subjects:
Antibiotics
Beta-lactam antibiotics
Carbapenem
Ceftazidime
Cephalosporin
EEG
Infants
Meropenem
Migrating focal seizures
Neurotoxicity
Penicillin
Seizures
β-Lactam antibiotics
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Summary:Seizures caused by beta-lactam antibiotics are relatively rare. However, they represent a clinically significant phenomenon and have been widely reported in all age groups. Here we describe two infants presenting subtle multifocal seizures with a migrating aspect on EEG during beta-lactam antibiotic treatment with agents from the carbapenem group (meropenem) and the cephalosporin group (ceftazidime).
ISSN:0987-7053
1769-7131
DOI:10.1016/j.neucli.2020.01.003