Recent Advances of Cell Membrane‐Coated Nanomaterials for Biomedical Applications

Surface modification of nanomaterials is essential for their biomedical applications owing to their passive immune clearance and damage to reticuloendothelial systems. Recently, a cell membrane‐coating technology has been proposed as an ideal approach to modify nanomaterials owing to its facile func...

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Bibliographic Details
Published in:Advanced functional materials 2020-09, Vol.30 (39), p.n/a
Main Authors: Liu, Wen‐Long, Zou, Mei‐Zhen, Qin, Si‐Yong, Cheng, Yin‐Jia, Ma, Yi‐Han, Sun, Yun‐Xia, Zhang, Xian‐Zheng
Format: Article
Language:English
Subjects:
Barriers
Biocompatibility
biomedical applications
Biomedical materials
Cell membranes
Cellular communication
Coating
immune responses
Materials science
Nanomaterials
Performance enhancement
targeting ability
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Summary:Surface modification of nanomaterials is essential for their biomedical applications owing to their passive immune clearance and damage to reticuloendothelial systems. Recently, a cell membrane‐coating technology has been proposed as an ideal approach to modify nanomaterials owing to its facile functionalized process and good biocompatibility for improving performances of synthetic nanomaterials. Here, recent advances of cell membrane‐coated nanomaterials are reviewed based on the main biological functions of the cell membrane in living cells. An overview of the cell membrane is introduced to understand its functions and potential applications. Then, the applications of cell membrane‐coated nanomaterials based on the functions of the cell membrane are summarized, including physical barrier with selective permeability and cellular communication via information transmission and reception processes. Finally, perspectives of biomedical applications and challenges about cell membrane‐coated nanomaterials are discussed. Recent advances of cell membrane‐coated nanomaterials are summarized here based on the main biological functions of the cell membrane, including physical barrier and cellular communication. Perspectives of biomedical applications and challenges of cell membrane‐coated nanomaterials are also discussed.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.202003559