Umbilical cord stem cells: Background, processing and applications

•Human umbilical cord stem cells (UCSCs) is currently attracting attention.•Advantages of UCSCs.•Methods of Processing of UCSCs.•Banking of UCSCs.•Applications of UCSCs. Stem cells have currently gained attention in the field of medicine not only due to their ability to repair dysfunctional or damag...

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Bibliographic Details
Published in:Tissue & cell 2020-08, Vol.65, p.101351, Article 101351
Main Authors: Alatyyat, Shumukh M., Alasmari, Houton M., Aleid, Omamah A., Abdel-maksoud, Mohamed S., Elsherbiny, Nehal
Format: Article
Language:English
Subjects:
Amnion
Applications
Autografts
Drug delivery
Drug delivery systems
Embryo cells
Fetuses
Medical treatment
Medicine
Placenta
Processing
Stem cells
Umbilical cord
Umbilical cord stem cells
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Summary:•Human umbilical cord stem cells (UCSCs) is currently attracting attention.•Advantages of UCSCs.•Methods of Processing of UCSCs.•Banking of UCSCs.•Applications of UCSCs. Stem cells have currently gained attention in the field of medicine not only due to their ability to repair dysfunctional or damaged cells, but also they could be used as drug delivery system after being engineered to do so. Human umbilical cord is attractive source for autologous and allogenic stem cells that are currently amenable to treatment of various diseases. Human umbilical cord stem cells are -in contrast to embryonic and fetal stem cells- ethically noncontroversial, inexpensive and readily available source of cells. Umbilical cord, umbilical cord vein, amnion/placenta and Wharton’s jelly are all rich of many types of multipotent stem cell populations capable of forming many different cell types. This review will focus on umbilical cord stem cells processing and current application in medicine.
ISSN:0040-8166
1532-3072
DOI:10.1016/j.tice.2020.101351