Dentin Tubule Occlusion Potential of Novel Dentifrices Having Fluoride Containing Bioactive Glass and Zinc Oxide Nanoparticles

Objective: To compare the in vitro potential of dentin tubule occlusion of two novel experimental dentifrices consisting of fluoride containing bioactive glass (BG) with zinc oxide nanoparticles. Materials and Methods: Forty-eight dentin discs (n = 48) were divided into 6 groups (n = 8), based on th...

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Bibliographic Details
Published in:Medical principles and practice 2020-07, Vol.29 (4), p.338-346
Main Authors: Khan, Abdul Samad, Farooq, Imran, Alakrawi, Kawther Moosa, Khalid, Hina, Saadi, Omar Waqas, Hakeem, Abbas Saeed
Format: Article
Language:English
Subjects:
Acids
Dentin
Enamel
Fluorides
Nanoparticles
Original Paper
Toothbrushes
Toothpaste
Zinc oxides
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Summary:Objective: To compare the in vitro potential of dentin tubule occlusion of two novel experimental dentifrices consisting of fluoride containing bioactive glass (BG) with zinc oxide nanoparticles. Materials and Methods: Forty-eight dentin discs (n = 48) were divided into 6 groups (n = 8), based on their brushing dentifrices: Group 1 = artificial saliva (AS; control); Group 2 = fluoride dentifrice (Colgate Palmolive © , UK); Group 3 = experimental nonactive agent dentifrice; Group 4 = experimental dentifrice with 1.5% BG; Group 5 = experimental dentifrice with 4% BG; and Group 6 = BioMinF © dentifrice. Postbrushing, the discs were subjected to acidic challenge with 6% wt citric acid (pH = 4.0) for 1 min. Scanning electron microscope (SEM) and energy-dispersive X-ray (EDX) spectroscopy were performed pre- and post-citric acid challenges, and percentages of tubule occlusion assessed. Results: SEM micrographs of group 1 (AS) show no tubule occlusion (0%), whereas those of groups 2 and 3 show partial tubule occlusion (25 to 50 and
ISSN:1011-7571
1423-0151
DOI:10.1159/000503706