Heater for Controlled Evaporation of Liquids for Personalized Drug Delivery to the Lungs

We examined the potential of thermal evaporation for the controlled production of aerosols for the administration of drugs to the lungs. A novel volumetric heater was designed and fabricated allowing better control of the heating power transferred to the solvent compared to conventional coil heaters...

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Bibliographic Details
Published in:Journal of microelectromechanical systems 2020-10, Vol.29 (5), p.984-989
Main Authors: Goldschmidtboeing, Frank, Pelz, Uwe, Ghanam, Muhannad, Bilger, Thomas, Jamali, Armin, Saberi, Mohammadreza, Baeumker, Eiko, Jaklin, Jan, Kessler, Marc, Schmidt, Rene, Schadow, David, Scheunemann, Patrick, Woias, Peter
Format: Article
Language:English
Subjects:
Aerosol generation
Aerosols
Cigarettes
Coils
drug delivery
Drug delivery systems
Drugs
Evaporation
Heating systems
Liquids
Lungs
personalized medicine
resistive heater
Semiconductor device measurement
Temperature distribution
Temperature measurement
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Summary:We examined the potential of thermal evaporation for the controlled production of aerosols for the administration of drugs to the lungs. A novel volumetric heater was designed and fabricated allowing better control of the heating power transferred to the solvent compared to conventional coil heaters that are commonly used in e-cigarettes. The whole silicon chip is used as a resistive heater. Therefore, we call this approach a volumetric heater. We demonstrate that the vapor production of the volumetric heater can be controlled over a wide dynamic range by varying the heater temperature. [2020-0105]
ISSN:1057-7157
1941-0158
DOI:10.1109/JMEMS.2020.3003467