Effectiveness of a pharmaceutical instruction video for adherence to dermatopathy treatment in patients with cancer receiving the anti-epidermal growth factor receptor antibody

Background Dermatopathy develops as a side effect in patients receiving anti-epidermal growth factor receptor antibody treatment. Topical moisturizers are used for the prevention and treatment of this dermatopathy. Active participation of patients in their own treatment is important for the appropri...

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Bibliographic Details
Published in:Journal of oncology pharmacy practice 2020-10, Vol.26 (7), p.1667-1675
Main Authors: Sato, Junya, Ishikawa, Hiroshi, Yasuda, Yoko, Tanaka, Rei, Kiyohara, Yoshio, Yamawaki, Yuki, Endo, Megumi, Shino, Michihiro
Format: Article
Language:English
Subjects:
Aged
Antibodies
Antineoplastic Agents - adverse effects
Epidermal growth factor
ErbB Receptors - antagonists & inhibitors
Female
Humans
Male
Medication Adherence
Middle Aged
Neoplasms - drug therapy
Patient compliance
Patient Education as Topic
Pharmaceuticals
Pharmacists
Side effects
Skin Diseases - drug therapy
Topical application
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Summary:Background Dermatopathy develops as a side effect in patients receiving anti-epidermal growth factor receptor antibody treatment. Topical moisturizers are used for the prevention and treatment of this dermatopathy. Active participation of patients in their own treatment is important for the appropriate application of topical preparations. We prepared a pharmaceutical instructional video for adhering to the topical application protocol. In this study, we investigated the effectiveness of this pharmaceutical instructional video on treatment adherence. Methods Study participants were patients with cancer receiving the anti-epidermal growth factor receptor antibody for the first time. A pharmacist instructed the patients on how to use the pharmaceutical instruction video. Daily topical preparation use following the video demonstration was assessed. The effectiveness of the pharmaceutical instruction video was evaluated by assessing the adherence of patients who did not use the pharmaceutical instruction video for the past 2 periods (26 months; controls 1 and 2). The incidence of side effects was compared between the two control groups and the group of patients who received the pharmaceutical instruction video. Results The amount of topical preparation consumed (median, g/day) by patients who received patient compliance instructions using the pharmaceutical instruction video was 9.8 g/day, as compared with control group 1 (4.5 g/day) and control group 2 (5.5 g/day) (p 
ISSN:1078-1552
1477-092X
DOI:10.1177/1078155220904149