New biologically active phosphonium salts based on 3-(diphenylphosphino)propionic acid and unsaturated amides

New carboxylate phosphabetaines were synthesized from 3-(diphenylphosphino)propionic acid and unsaturated amides. Alkylation of the synthesized carboxylate phosphabetaines with haloalkyles was studied. In vitro biological activity of the synthesized phosphonium salts was evaluated.

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Bibliographic Details
Published in:Russian chemical bulletin 2020-08, Vol.69 (8), p.1569-1572
Main Authors: Bakhtiyarova, Yu. V., Morozov, M. V., Romanov, S. R., Minnullin, R. R., Shulaeva, M. P., Pozdeev, O. K., Galkina, I. V., Galkin, V. I.
Format: Article
Language:English
Subjects:
Alkylation
Amides
Biological activity
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Full Articles
Inorganic Chemistry
Organic Chemistry
Propionic acid
Synthesis
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Description
Summary:New carboxylate phosphabetaines were synthesized from 3-(diphenylphosphino)propionic acid and unsaturated amides. Alkylation of the synthesized carboxylate phosphabetaines with haloalkyles was studied. In vitro biological activity of the synthesized phosphonium salts was evaluated.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-020-2936-y