Efficient Synthesis of Pyrido[2,3-d]pyrimidines by Recyclization of N-Arylitaconimides with Aminopyrimidinones

A convenient method has been proposed for the synthesis of 2-(4,7-dioxopyrido[2,3- d ]pyrimidin-6-yl)acetanilides and 2-(2,4,7-trioxopyrido[2,3- d ]pyrimidin-6-yl)acetanilides via reaction of N -arylitaconimides with 6-aminopyrimidin-4(3 H )-ones and 6-aminopyrimidine-2,4(1 H ,3 H )-diones, respecti...

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Published in:Russian journal of organic chemistry 2020-09, Vol.56 (9), p.1512-1518
Main Authors: Shmoylova, Y. U., Kovygin, Yu. A., Vandyshev, D. Yu, Ledenyova, I. V., Kosheleva, E. A., Shikhaliev, Kh. S.
Format: Article
Language:English
Subjects:
Acetic acid
Chemistry
Chemistry and Materials Science
Diketones
Organic Chemistry
Pyrimidines
Synthesis
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creator Shmoylova, Y. U.
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description A convenient method has been proposed for the synthesis of 2-(4,7-dioxopyrido[2,3- d ]pyrimidin-6-yl)acetanilides and 2-(2,4,7-trioxopyrido[2,3- d ]pyrimidin-6-yl)acetanilides via reaction of N -arylitaconimides with 6-aminopyrimidin-4(3 H )-ones and 6-aminopyrimidine-2,4(1 H ,3 H )-diones, respectively, in boiling acetic acid.
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subjects Acetic acid
Chemistry
Chemistry and Materials Science
Diketones
Organic Chemistry
Pyrimidines
Synthesis
title Efficient Synthesis of Pyrido[2,3-d]pyrimidines by Recyclization of N-Arylitaconimides with Aminopyrimidinones
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