Sox15 T/G may be a candidate gene polymorphism for athlete performance

Muscle formation and regeneration are critical factors for athlete endurance performance, and the SOX15 gene is one of the important genes for muscle formation and regeneration. Although there are many studies on the relationship between the SOX15 gene and muscle tissue, there are few studies on the...

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Bibliographic Details
Published in:Journal of Physical Education and Sport 2020-09, Vol.20 (5), p.2614-2619
Main Authors: Subak, Erdem, Muniroglu, Surhat
Format: Article
Language:English
Subjects:
Athletes
Cell cycle
College Science
Control Groups
Deoxyribonucleic acid
DNA
DNA polymerase
Genes
Individualized Instruction
Injuries
Males
Musculoskeletal system
Polymorphism
Soccer
Sports injuries
Statistical analysis
Team Sports
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Summary:Muscle formation and regeneration are critical factors for athlete endurance performance, and the SOX15 gene is one of the important genes for muscle formation and regeneration. Although there are many studies on the relationship between the SOX15 gene and muscle tissue, there are few studies on the relationship between the SOX15 gene and athlete performance relation are very limited number. This study aimed to analyse the SOX15 T/G (rs4227) polymorphisms of soccer referees, who performed 3000 m and above in the Cooper test, and of the control group. For this purpose, 30 male soccer referees, who performed 3000 m and above in the Cooper test, were selected. For the control group, 30 male participants without a sportsman license were selected. In addition, in this study, ACE I/D (rs4646994) and HGF C/A (rs5745697) polymorphisms were analysed. The results showed a statistically significant difference in SOX15 T/G (χ2 = 10.24, p = 0.006) between the referees and the control group. The SOX15 T allele showed a significantly higher frequency in soccer referees than in the control group. However, our data did not show statistically significant differences in ACE I/D and HGF C/A. Our results suggested that SOX15 T/G polymorphism could be related to the endurance performance of athletes.
ISSN:2247-8051
2247-806X
DOI:10.7752/jpes.2020.05356