Ufasomes: A Potential Vesicular Carrier System

Vesicular drug delivery system sustains the drug action at a predetermined rate. [...]it maintains an efficient drug level in the body, and simultaneously minimizes the undesirable side effects. [3, 7] Keywords: Fatty Acid Vesicles, Lipid film hydration, Oleic acid, Ufasome, Vesicular Drug Delivery...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2020-10, Vol.12 (10), p.1332-1335
Main Authors: Lakshmi, V Sree, Manohar, R Deepa, Mathan, S, Dharan, Shaiju S
Format: Article
Language:English
Subjects:
Drug delivery systems
Drugs
Efficiency
Fatty acids
Hydration
Hydrocarbons
Lipids
Morphology
Particle size
Skin
Spectrum analysis
Thin films
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Summary:Vesicular drug delivery system sustains the drug action at a predetermined rate. [...]it maintains an efficient drug level in the body, and simultaneously minimizes the undesirable side effects. [3, 7] Keywords: Fatty Acid Vesicles, Lipid film hydration, Oleic acid, Ufasome, Vesicular Drug Delivery System INTRODUCTION Ufasomes are vesicles of long chain unsaturated fatty acids obtained as a result of mechanical agitation of evaporated film in the presence of buffer solution. The fatty acid vesicles can be formed not only from unsaturated fatty acids such as oleic acid, linoleic acid, but also from saturated fatty acid such as octanoic acid and decanoic acid. At the end, a thin film of fatty acid is formed which is hydrated with buffer of appropriate pH. * By Addition Of Alcohol In this method, formation of fatty acid vesicles is by the addition of alcohol having the same chain length as that of fatty acid.
ISSN:0975-1459