Metformin in pregnancy

Metformin is an oral insulin-sensitizing anti-diabetic drug. Polycystic ovary syndrome (PCOS) and gestational diabetes (GDM) are both associated with insulin resistance and hyperinsulinemia. Metformin can bring potential benefits in pregnant women due to its favorable metabolic effect. Nevertheless,...

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Bibliographic Details
Published in:Ginekologia polska 2014-01, Vol.85 (7), p.527
Main Authors: Bijok, Julia, Bińkowska, Małgorzata, Jakiel, Grzegorz
Format: Article
Language:eng ; pol
Subjects:
Antidiabetics
Diabetes, Gestational - drug therapy
Female
Humans
Hypoglycemic Agents - adverse effects
Hypoglycemic Agents - therapeutic use
Insulin Resistance
Metformin - adverse effects
Metformin - pharmacology
Metformin - therapeutic use
Polycystic Ovary Syndrome - drug therapy
Pregnancy
Pregnancy Outcome
Prenatal Exposure Delayed Effects
Treatment Outcome
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Summary:Metformin is an oral insulin-sensitizing anti-diabetic drug. Polycystic ovary syndrome (PCOS) and gestational diabetes (GDM) are both associated with insulin resistance and hyperinsulinemia. Metformin can bring potential benefits in pregnant women due to its favorable metabolic effect. Nevertheless, there is a possibility of adverse effects on the fetus as metformin crosses the placenta. In this review we discuss safety and indications for metformin administration in pregnancy.
ISSN:0017-0011
0017-0011
2543-6767
DOI:10.17772/gp/1765