Study the possibility of theoretically reducing the number of radiation sessions for patients with skin cancer using nanoparticles

• Main Authors: Abdulwahid, Talib A., Bakir, Hussien A. A., Alsabari, Imad K.
• Format: Conference Proceeding
• Language: English
• Subjects: Cancer; Contrast agents; Electron beams; Electron energy; Nanoparticles; Nanotechnology; Radiation therapy; Reduction; Sensitivity enhancement; Silver; Skin cancer
• ISSN: 0094-243X; 1551-7616
• DOI: 10.1063/5.0027548

The reduction in the number of sessions of radiotherapy is a primary goal in the field of radiotherapy. An important and promising approach to reach this goal is using the nanotechnology. This is via employing nanoparticles as a contrast agent to the target where radiation is applied. The contribution of the nanoparticles is expected to improve the sensitivity enhancement ratio (SER). The best way of exploiting the nanotechnology is by through the silver nanoparticles (AgNPs) together with electron beam. The role of AgNPs is to increase the probability of the absorption of electrons within the tumor region while maintaining the adjacent healthy tissue unaffected. This therefore led to an increase in the destruction of cancer cells. In this work, the (AgNPs) were used as a contrast agent for skin cancer treatment with electron energy ranged from 2 MeV to 15 MeV. The findings demonstrated that there is an increase in the SER (e.g. 1.3 times with energy of 15 MeV). This would indicate for a reduction in the number of the required sessions ranged from four to five weeks period based on the applied energy of electrons where the ordinary radiotherapy sessions are known to be around seven weeks.