Acute myocardial dysfunction in lupus: outcomes in Asian Indians

Background Acute myocardial dysfunction is an uncommon but potentially fatal complication in systemic lupus erythematosus (SLE). We describe the outcome in a small series of Asian Indian patients and examine associated factors. Methods SLE patients who fulfilled the 2012 SLICC criteria and developed...

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Bibliographic Details
Published in:Clinical rheumatology 2020-12, Vol.39 (12), p.3661-3667
Main Authors: Dhooria, Aadhaar, Gawalkar, Atit, Santosh, Krishna, Bahl, Ajay, MB, Adarsh, Naidu, GSRSNK, Sharma, Shefali, Sharma, Aman, Jain, Sanjay, Dhir, Varun
Format: Article
Language:English
Subjects:
Adolescent
Adult
Complement component C3
Corticosteroids
Cyclophosphamide
Echocardiography
Ejection fraction
Heart
Humans
Immunosuppression
Infections
Lupus
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - drug therapy
Medicine
Medicine & Public Health
Methylprednisolone
Mortality
Original Article
Procalcitonin
Retrospective Studies
Rheumatology
Sepsis
Stroke Volume
Survival analysis
Systemic lupus erythematosus
Ventricle
Ventricular Function, Left
Young Adult
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Summary:Background Acute myocardial dysfunction is an uncommon but potentially fatal complication in systemic lupus erythematosus (SLE). We describe the outcome in a small series of Asian Indian patients and examine associated factors. Methods SLE patients who fulfilled the 2012 SLICC criteria and developed new-onset myocardial dysfunction were included in this retrospective case series. Acute myocardial dysfunction was defined as global hypokinesia and left ventricular ejection fraction (LVEF)
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-020-05177-2