Polysaccharide-coated iron oxide nanoparticles: Synthesis, properties, surface modification

•Magnetite nanoparticles coated with arabinogalactan and chitosan were synthesized.•Immobilization of biospecific molecules on the nanoparticle surface was studied.•The obtained samples are characterized by a high density of immobilized molecules.•Such nanoparticles can be used in bioanalytical syst...

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Bibliographic Details
Published in:Materials letters 2021-02, Vol.284, p.128920, Article 128920
Main Authors: Stolyar, S.V., Krasitskaya, V.V., Frank, L.A., Yaroslavtsev, R.N., Chekanova, L.A., Gerasimova, Y.V., Volochaev, M.N., Bairmani, M.Sh, Velikanov, D.A.
Format: Article
Language:English
Subjects:
Biomaterials
Chitosan
Immobilization
Iron oxides
Magnetic materials
Magnetic properties
Materials science
Nanoparticles
Polysaccharide
Polysaccharides
Sorbents
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Summary:•Magnetite nanoparticles coated with arabinogalactan and chitosan were synthesized.•Immobilization of biospecific molecules on the nanoparticle surface was studied.•The obtained samples are characterized by a high density of immobilized molecules.•Such nanoparticles can be used in bioanalytical systems or as affinity sorbents. In this work, magnetite nanoparticles coated with polysaccharides were synthesized. Arabinogalactan and chitosan were used as polysaccharides. The possibilities of immobilization of biospecific molecules on the surface of the obtained composites were studied. Experiments on covalent immobilization of biospecific molecules on magnetic nanoparticles coated with a polysaccharide showed a high density of immobilized molecules. This suggests the use of such materials in bioanalytical systems or as affinity sorbents.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2020.128920