A case of nasal septal perforation caused by bevacizumab for advanced cervical cancer

Nasal septal perforation caused by bevacizumab is rarely reported in other cancers such as ovarian cancer and breast cancer, but it has not been reported in cervical cancer. A 48‐year‐old woman with a medical history of chronic allergic rhinitis was diagnosed stage 4B (T2bN1M0) cervical cancer and p...

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Bibliographic Details
Published in:The journal of obstetrics and gynaecology research 2021-02, Vol.47 (2), p.833-837
Main Authors: Taira, Yusuke, Shimoji, Yuko, Nakasone, Tadaharu, Arakaki, Yoshihisa, Nakamoto, Tomoko, Kudaka, Wataru, Aoki, Yoichi
Format: Article
Language:English
Subjects:
Allergic rhinitis
Bevacizumab
Breast cancer
Carboplatin
Cervical cancer
Cervix
Chemotherapy
Immunotherapy
Monoclonal antibodies
nasal septal perforation
Ovarian cancer
Paclitaxel
Targeted cancer therapy
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Summary:Nasal septal perforation caused by bevacizumab is rarely reported in other cancers such as ovarian cancer and breast cancer, but it has not been reported in cervical cancer. A 48‐year‐old woman with a medical history of chronic allergic rhinitis was diagnosed stage 4B (T2bN1M0) cervical cancer and paclitaxel and carboplatin along with bevacizumab (triweekly) were administered. After eight courses of chemotherapy, nasal septal perforation was noted. The possibility of nasal septal perforation by bevacizumab was considered by excluding other causes. We report the first case of nasal septal perforation caused by bevacizumab for advanced cervical cancer.
ISSN:1341-8076
1447-0756
DOI:10.1111/jog.14589