Structure and Properties Characterization of Amphiphilic Dendrons Modified Lipid Membrane

Coassembly of lipids and polyamidoamine amphiphilic dendrons (AD) is expected to provide desirable characteristics to drug delivery carriers. However, there have been few studies about structure and properties of these coassemblies. In this study, coassemblies (lipid-AD) were prepared by different g...

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Bibliographic Details
Published in:Chemistry letters 2021-01, Vol.50 (1), p.187-190
Main Authors: Han, Jin, Iimure, Yosuke, Okamoto, Yukihiro, Suga, Keishi, Umakoshi, Hiroshi
Format: Article
Language:English
Subjects:
Hydration
Lipids
Properties (attributes)
Structural analysis
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Summary:Coassembly of lipids and polyamidoamine amphiphilic dendrons (AD) is expected to provide desirable characteristics to drug delivery carriers. However, there have been few studies about structure and properties of these coassemblies. In this study, coassemblies (lipid-AD) were prepared by different generation and composition ratio of AD, and then the structure and their properties were characterized, especially fluidity and hydration state. In conclusion, generation of AD showed significant influence on coassembly structure and hydration state.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.200633