Impact of both socioeconomic level and occupational nature on the antibody prevalence to SARS‐CoV‐2 in an Egyptian cohort: the first episode

• Published in: Journal of Medical Virology 2021
• Main Authors: Mahmoud Mohamed Bahgat, Nadeem, Rola, Mohamed Hassan Nasraa, Mona Abd‐Elkader Awad, Kamel, Solaf, Dina Nadeem Abd‐Elshafy
• Format: Web Resource
• Language: English
• DOI: 10.1002/jmv.26852

We studied impact of socioeconomic level on the anti‐SARS‐CoV‐2‐antibodies prevalence in an Egyptian cohort. The low socioeconomic standard group (LSS) included 51 humans, 30 females (F) and 21 males (M). The high socioeconomic standard group (HSS) included 55 subjects, 24 F and 31 M. Of the 30 LSSF, 6 were IgM, 21 IgG and 6 double positive. Of the 21 LSSM, 5 were IgM, 12 IgG and 5 double positive. Of the 24 HSSF, 6 were IgM, 11 IgG and 5 double positive. Of the 31 HSSM, 6 were IgM, 14 IgG and 4 double positive. Of the 51 LSS humans, 26 were symptomatic (S) and 25 asymptomatic (AS). Of the 26 S, 20 were IgG and 8 IgM/gG double positive. Of the 25 AS, 13 were IgG and 3 IgM/IgG double positive. Of the 55 HSS humans, 38 were S and 17 AS. Of the 38 S, 24 were IgG and 11 IgM positive of whom, 9 were double positive. Of the 17 AS, one was IgG and one IgM positive. The IgM prevalence was higher among the HSS humans. The IgG prevalence was significantly higher among the LSS humans. In the two different socioeconomic standards, the prevalence of either IgM or IgG was higher among F. Inverse correlation was observed between the age and the anti‐SARS‐CoV‐2‐antibodies prevalence except for LSSF‐IgG and LSSM‐IgM. In conclusion, socioeconomic standard, gender and age impact humoral responses to SARS‐CoV‐2 with a clear heterogeneity in individualized responses to the infection in terms of symptoms.