Catheter ablation of premature ventricular contractions originating from periprosthetic aortic valve regions

Background Little is known about the ablation outcomes of premature ventricular contractions (PVCs) that originate from the periprosthetic aortic valve (PPAV) regions of patients with aortic valve replacement (AVR). Methods and Results Our study had 11 patients who underwent catheter ablation for PV...

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Bibliographic Details
Published in:Journal of cardiovascular electrophysiology 2021-02, Vol.32 (2), p.400-408
Main Authors: Han, Jie, Lee, Justin Z., Padmanabhan, Deepak, Naksuk, Niyada, Asirvatham, Samuel J., Munger, Thomas M., Killu, Ammar M., Madhavan, Malini, Xiao, PeiLin, Zheng, Liang‐Rong, Cha, Yong‐Mei
Format: Article
Language:English
Subjects:
Ablation
Aortic valve
atrioventricular conduction
Catheters
Echocardiography
Ejection fraction
Fluoroscopy
Heart
left ventricle outflow tract
premature ventricular contraction
Prostheses
prosthetic valve
Radiofrequency ablation
radiofrequency catheter ablation
Regurgitation
Ventricle
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Summary:Background Little is known about the ablation outcomes of premature ventricular contractions (PVCs) that originate from the periprosthetic aortic valve (PPAV) regions of patients with aortic valve replacement (AVR). Methods and Results Our study had 11 patients who underwent catheter ablation for PVCs arising from the PPAV regions (bioprosthetic aortic valve, n = 5; mechanical aortic valve, n = 6). The PVC characteristics, procedure characteristics, and efficacy of ablation were compared with the control group (n = 33). At baseline, the PPAV group had a lower left ventricular ejection fraction (mean [SD], 41% [12%] vs. 51% [8%]; p = .002). The rate of acute ablation success was 90.9% in the PPAV group. Ablation sites were identified above the left coronary cusp (LCC) and right coronary cusp commissure (LRCC) in one PVC, below the prosthetic valve in eight PVCs (four below LCC and four below LRCC), and within the distal coronary sinus in two PVCs. The mean procedure time, fluoroscopy time, and radiation in the PPAV group were all significantly greater than those in the control group (all p 
ISSN:1045-3873
1540-8167
DOI:10.1111/jce.14836