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Chronic severe methanol intoxication after repeated mask cleansing for fear to COVID‐19 – a new risk of coronaphobia

Background Disproportionate fear to contract COVD‐19 (coronaphobia) may result in inappropriate use of preventive measures that could, in turn, result in severe damage to the patient. Objective To describe a patient with subacute parkinsonism and cognitive dysfunction and MRI evidence of bilateral d...

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Published in:European Journal of Neurology 2021
Main Authors: Markel Erburu‐Iriarte, Patricia Rodrigo‐Armenteros, Iñigo Oyarzun‐Irazu, Ines Aranzabal‐Alustiza, Saul Silvarrey‐Rodriguez, Lander Antón‐Méndez, Juan Carlos García‐Moncó
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container_title European Journal of Neurology
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creator Markel Erburu‐Iriarte
Patricia Rodrigo‐Armenteros
Iñigo Oyarzun‐Irazu
Ines Aranzabal‐Alustiza
Saul Silvarrey‐Rodriguez
Lander Antón‐Méndez
Juan Carlos García‐Moncó
description Background Disproportionate fear to contract COVD‐19 (coronaphobia) may result in inappropriate use of preventive measures that could, in turn, result in severe damage to the patient. Objective To describe a patient with subacute parkinsonism and cognitive dysfunction and MRI evidence of bilateral deep white matter and basal ganglia damage. Case presentation A 56‐year‐old female presented with a 4‐week history of insomnia, cognitive decline, and parkinsonism. Brain MRI revealed a bilateral lesion of both globus pallidus, deep white matter, and cerebellar hemispheres. Her son informed that, for the previous month, she had been cleaning her facial mask 3 times a day with a pure methanol solution as a disinfectant for an intense fear of acquiring COVID‐19. Previously, she had used 97% isopropyl alcohol and inadvertently switched to methanol. After exposure ended, she slowly improved but 4 months later she remains severely disabled. Conclusions The repeated exposure to methanol vapor, the MRI findings and the absence of other aetiologies for her cognitive and parkinsonian features led to the diagnosis of chronic methanol intoxication with severe central nervous system damage. Misinformation is a likely contributory factor to these situations. Efforts should be made by the scientific community to avoid self‐damaging behaviours as a result of coronaphobia.
doi_str_mv 10.1111/ene.14779
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Objective To describe a patient with subacute parkinsonism and cognitive dysfunction and MRI evidence of bilateral deep white matter and basal ganglia damage. Case presentation A 56‐year‐old female presented with a 4‐week history of insomnia, cognitive decline, and parkinsonism. Brain MRI revealed a bilateral lesion of both globus pallidus, deep white matter, and cerebellar hemispheres. Her son informed that, for the previous month, she had been cleaning her facial mask 3 times a day with a pure methanol solution as a disinfectant for an intense fear of acquiring COVID‐19. Previously, she had used 97% isopropyl alcohol and inadvertently switched to methanol. After exposure ended, she slowly improved but 4 months later she remains severely disabled. Conclusions The repeated exposure to methanol vapor, the MRI findings and the absence of other aetiologies for her cognitive and parkinsonian features led to the diagnosis of chronic methanol intoxication with severe central nervous system damage. Misinformation is a likely contributory factor to these situations. Efforts should be made by the scientific community to avoid self‐damaging behaviours as a result of coronaphobia.</description><identifier>DOI: 10.1111/ene.14779</identifier><language>eng</language><publisher>Hoboken: John Wiley &amp; Sons, Inc</publisher><ispartof>European Journal of Neurology, 2021</ispartof><rights>2021. 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Objective To describe a patient with subacute parkinsonism and cognitive dysfunction and MRI evidence of bilateral deep white matter and basal ganglia damage. Case presentation A 56‐year‐old female presented with a 4‐week history of insomnia, cognitive decline, and parkinsonism. Brain MRI revealed a bilateral lesion of both globus pallidus, deep white matter, and cerebellar hemispheres. Her son informed that, for the previous month, she had been cleaning her facial mask 3 times a day with a pure methanol solution as a disinfectant for an intense fear of acquiring COVID‐19. Previously, she had used 97% isopropyl alcohol and inadvertently switched to methanol. After exposure ended, she slowly improved but 4 months later she remains severely disabled. Conclusions The repeated exposure to methanol vapor, the MRI findings and the absence of other aetiologies for her cognitive and parkinsonian features led to the diagnosis of chronic methanol intoxication with severe central nervous system damage. Misinformation is a likely contributory factor to these situations. 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Objective To describe a patient with subacute parkinsonism and cognitive dysfunction and MRI evidence of bilateral deep white matter and basal ganglia damage. Case presentation A 56‐year‐old female presented with a 4‐week history of insomnia, cognitive decline, and parkinsonism. Brain MRI revealed a bilateral lesion of both globus pallidus, deep white matter, and cerebellar hemispheres. Her son informed that, for the previous month, she had been cleaning her facial mask 3 times a day with a pure methanol solution as a disinfectant for an intense fear of acquiring COVID‐19. Previously, she had used 97% isopropyl alcohol and inadvertently switched to methanol. After exposure ended, she slowly improved but 4 months later she remains severely disabled. Conclusions The repeated exposure to methanol vapor, the MRI findings and the absence of other aetiologies for her cognitive and parkinsonian features led to the diagnosis of chronic methanol intoxication with severe central nervous system damage. Misinformation is a likely contributory factor to these situations. Efforts should be made by the scientific community to avoid self‐damaging behaviours as a result of coronaphobia.</abstract><cop>Hoboken</cop><pub>John Wiley &amp; Sons, Inc</pub><doi>10.1111/ene.14779</doi></addata></record>
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title Chronic severe methanol intoxication after repeated mask cleansing for fear to COVID‐19 – a new risk of coronaphobia
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