[3+2]-Dipolar Cycloaddition of Nitrones to Pyrroloquinoxalinetriones

[3+2]-Dipolar cycloaddition of diarylnitrones to substituted pyrroloquinoxalinetriones afforded (2a S *,3 R *,5a S *)-2a-acyl-3,4-diaryl-3,4-dihydro-1 H -[1,2]oxazolo[5′,4′:2,3]pyrrolo[1,2- a ]quinoxaline-1,2,6(2a H ,7 H )-triones that attract interest for medicinal chemistry.

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Bibliographic Details
Published in:Russian journal of organic chemistry 2021, Vol.57 (1), p.32-37
Main Authors: Stepanova, E. E., Dmitriev, M. V., Maslivets, A. N.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Cycloaddition
Organic Chemistry
Quinoxalines
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Description
Summary:[3+2]-Dipolar cycloaddition of diarylnitrones to substituted pyrroloquinoxalinetriones afforded (2a S *,3 R *,5a S *)-2a-acyl-3,4-diaryl-3,4-dihydro-1 H -[1,2]oxazolo[5′,4′:2,3]pyrrolo[1,2- a ]quinoxaline-1,2,6(2a H ,7 H )-triones that attract interest for medicinal chemistry.
ISSN:1070-4280
1608-3393
DOI:10.1134/S107042802101005X