Comparative phytochemical, antioxidant and antibacterial potentials of the stem, roots and leaves extract of Chromolaena Odorata l. (King and Robinson)

The stem, root and leaves of Chromolaena odorata were extracted using distilled ethanol (95%). The ethanolic extracts were then screened for their phytochemical, antibacterial and antioxidant capacities. Phytochemical analysis revealed that the stem extract contained terpenoids, glycosides and resin...

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Bibliographic Details
Published in:Journal of pharmaceutical and biological sciences 2015-07, Vol.3 (4), p.202
Main Authors: Afolayan, Michael, Fatokun Olakunle, Olutayo, Olajide, Jubril, Akolade, Adebisi, Fagbohun, Orishadipe Abayomi
Format: Article
Language:English
Subjects:
Alkaloids
Antioxidants
Ascorbic acid
Cardiac glycosides
Clinical isolates
Ethanol
Flavonoids
Glycosides
Leaves
Minimum inhibitory concentration
Phytochemicals
Plant extracts
Resins
Saponins
Steroid hormones
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Summary:The stem, root and leaves of Chromolaena odorata were extracted using distilled ethanol (95%). The ethanolic extracts were then screened for their phytochemical, antibacterial and antioxidant capacities. Phytochemical analysis revealed that the stem extract contained terpenoids, glycosides and resins , while the root extract contained alkaloids, tannins, cardiac glycosides and balsam and the leaves extract contained terpenoids, steroids, phenols, alkaloids, flavonoids, cardiac glycosides and saponins. Antibacterial activities were evaluated against four clinical isolates using agar well diffusion method. The results indicated that the leaf extract was the most active against all tested microorganisms with the minimum inhibitory concentration (MIC) ranging from 7.81 31.25 g/ml while the stem extract was the least active with MIC values > 250 g/ml. Concentrations of the stem, root, leaf extracts and Vitamin C required for 50% inhibition of DPPH radical scavenging effect (IC50) were recorded as1.73, 0.73, 0.32 and 0.14 mg/ml respectively.
ISSN:2320-1924