Linitis plastica-type adenocarcinoma of the esophagus: a case report

“Linitis plastica” refers to a histological characterization of diffusely infiltrating, poorly differentiated adenocarcinoma. Linitis plastica-type esophageal adenocarcinoma is extremely rare: this is thought to be only the sixth case report of linitis plastica involving the esophagus. A 60-year-old...

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Bibliographic Details
Published in:Esophagus : official journal of the Japan Esophageal Society 2010-12, Vol.7 (4), p.225-229
Main Authors: Honda, Michitaka, Izumi, Yosuke, Miura, Akinori, Kato, Tsuyoshi, Momma, Kumiko, Horiguchi, Shinichiro, Nemoto, Tetsuo, Funada, Nobuaki, Nakajima, Hirotaka, Nagahama, Ryuji, Yoshida, Misao
Format: Article
Language:English
Subjects:
Case Report
Case reports
Chemotherapy
Dysphagia
Endoscopy
Esophageal cancer
Esophagus
Gastroenterology
Gastroesophageal reflux
Medical diagnosis
Medical prognosis
Medicine
Medicine & Public Health
Surgical Oncology
Thoracic Surgery
Throat surgery
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Summary:“Linitis plastica” refers to a histological characterization of diffusely infiltrating, poorly differentiated adenocarcinoma. Linitis plastica-type esophageal adenocarcinoma is extremely rare: this is thought to be only the sixth case report of linitis plastica involving the esophagus. A 60-year-old man was referred to our hospital after repeated endoscopic examinations over the course of a few months. Because he complained of dysphagia, upper endoscopy was performed, revealing stenosis with a few mucosal changes of the lower esophagus. Gastroesophageal reflux disease was initially diagnosed, but biopsy revealed adenocarcinoma. At the time of operation, peritoneal metastasis was noted. Macroscopically, the lesion was diffusely infiltrating, almost completely covered with normal squamous epithelium that showed positive staining with iodine. Pathological examination showed poorly differentiated adenocarcinoma. Despite the poor prognosis, the patient survived a comparatively long 18 months following esophagectomy with oral chemotherapy using S-1.
ISSN:1612-9059
1612-9067
DOI:10.1007/s10388-010-0248-2