Electrodeposition of Thiolated Polymer-based Hydrogels via Disulfide Formation Using Electrogenerated Benzoquinone

We present an electrodeposition method for fabricating thiolated polymer-based hydrogels through oxidation of hydroquinone (HQ). HQ is oxidized to benzoquinone (BQ) at an electrode, and the generated BQ is utilized for disulfide formation through an electrocatalytic reaction. As a simple demonstrati...

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Bibliographic Details
Published in:Chemistry letters 2021-02, Vol.50 (2), p.256-259
Main Authors: Ino, Kosuke, Tamura, Ayako, Hiramoto, Kaoru, Fukuda, Mika T, Nashimoto, Yuji, Shiku, Hitoshi
Format: Article
Language:English
Subjects:
Benzoquinone
Electrodeposition
Glucose oxidase
Hydrogels
Hydroquinone
Oxidation
Polymers
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Summary:We present an electrodeposition method for fabricating thiolated polymer-based hydrogels through oxidation of hydroquinone (HQ). HQ is oxidized to benzoquinone (BQ) at an electrode, and the generated BQ is utilized for disulfide formation through an electrocatalytic reaction. As a simple demonstration of bioapplications, an electrodeposited hydrogel containing glucose oxidase was applied for glucose sensing. To the best of our knowledge, this is the first report on the electrodeposition of thiolated polymer-based hydrogels via disulfide formation using the indirect approach.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.200732