Serum Erythropoietin, Interleukin-4, Ferritine, Iron, Total Iron Binding Capacity, Vitamin B12, Folate Levels in Patients with Behçet’s Disease

Background: Erythropoietin (EPO) is a naturally occurring hormone, produced in the kidneys, which stimulates the body to produce more red blood cells. Our purpose was to investigate EPO, IL-4 levels, and hematologic parameters including total blood count, iron, total iron binding capacity, ferritin,...

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Bibliographic Details
Published in:Journal of the Turkish Academy of Dermatology 2011-12, Vol.5 (4)
Main Authors: Türsen, Ümit, Çimen, Burak, Hale Api, Erçetin, Neslihan, Baz, Kıymet, İkizoğlu, Güliz, Atik, Uğur
Format: Article
Language:English
Subjects:
Blood tests
Erythrocytes
Vein & artery diseases
Vitamin B
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Summary:Background: Erythropoietin (EPO) is a naturally occurring hormone, produced in the kidneys, which stimulates the body to produce more red blood cells. Our purpose was to investigate EPO, IL-4 levels, and hematologic parameters including total blood count, iron, total iron binding capacity, ferritin, transferring, vitamin B-12, folate levels in patients with Behçet’s disease (BD). Material and Methods: Twenty patients with BD and 21 healthy volunteers were included in the study. Quantitative determination of EPO and IL-4 were determined with test kits by photometric ELISA method. Results: We found a significant increase in EPO and folate levels, whereas serum iron levels decreased in patients with BD. The distribution of IL-4, total blood count, total iron binding capacity, ferritin, transferrine, vitamin B-12 levels were the same in both groups. Conclusion: Patients with BD demonstrated higher EPO and folate levels, and lower serum iron levels. We conclude that higher EPO, folat levels may reflect a lower risk factor for systemic involvement of BD.
ISSN:1307-394X