Synthesis and characterization of novel mono, bis and tris heteroaryl chalcone derivatives of 1,3,5-trimethoxybenzene

In this study, a new series consisting of 12 heteroaryl chalcone derivatives of 1,3,5-trimethoxybenzene were synthesised. Chalcones were synthesised in high purity and efficiency, via condensation of mono, bis and tris 2,4,6-trimethoxy acetophenones with hetero-2-carbaldehyde derivatives based on Cl...

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Bibliographic Details
Published in:Organic communications 2021-01, Vol.14 (1), p.39-47
Main Authors: Polat, M. Fatih, Aktaş Anı, Derya
Format: Article
Language:English
Subjects:
Chemical analysis
Condensates
Infrared analysis
NMR
Nuclear magnetic resonance
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Summary:In this study, a new series consisting of 12 heteroaryl chalcone derivatives of 1,3,5-trimethoxybenzene were synthesised. Chalcones were synthesised in high purity and efficiency, via condensation of mono, bis and tris 2,4,6-trimethoxy acetophenones with hetero-2-carbaldehyde derivatives based on Claisen Schdmit condensation. The reactions feature a good scope for the all products, mild reaction conditions and good yields. The synthesized compounds were characterized by using FT-IR, NMR and elemental analysis spectroscopic techniques.
ISSN:1307-6175
1307-6175
DOI:10.25135/acg.oc.95.21.01.1942