The Toxicity of n-Hexane, Ethyl Acetate and Ethanol Extracts of SarangBanua (Clerodendrumfragrans Vent Willd) Leaves by Brine Shrimp Lethality Test (BSLT) Method

Sarangbanua traditional medicinal plant is found in Simalungunand NorthTapanuli Regencies, Sumatera, Indonesia. The result of plant determination, sarangbanuais Clerodendrumfragrans Vent Willd, including the Verbenaceae family. This study aims to determine the toxicity of the three types of leaf ext...

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Bibliographic Details
Published in:Journal of physics. Conference series 2021-03, Vol.1811 (1), p.12053
Main Authors: Simorangkir, Murniaty, Nainggolan, Bajoka, Juwitaningsih, Tita, Silaban, Saronom
Format: Article
Language:English
Subjects:
Biocompatibility
Brines
Ethanol
Ethyl acetate
Herbal medicine
Hexanes
Lethality
Physics
Toxicity
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Summary:Sarangbanua traditional medicinal plant is found in Simalungunand NorthTapanuli Regencies, Sumatera, Indonesia. The result of plant determination, sarangbanuais Clerodendrumfragrans Vent Willd, including the Verbenaceae family. This study aims to determine the toxicity of the three types of leaf extracts of C. fragrans Vent Will. The Brine Shrimp Lethality Test (BSLT) method was used to determine the toxicity of the extracts. The mortality data were then analyzed by Probit SAS to obtain LC 50 values. The results showed that the three types of C. fragrans leaf extracts had LC 50 values below 1000 µg/mL, so they were classified as toxic and potentially bioactive. The LC5 0 values of each of the ethanol, ethyl acetate and ethanol extracts were 26.25; 37.50 and 41.97 µg/mL
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1811/1/012053